Question

Diets that severely restrict carbohydrate intake often result in ketosis for the dieter.

Explain why this occurs by selecting the correct answer.

A. When carbohydrates are restricted, the body metabolizes fats for energy, resulting in a quantity of acetyl-CoA that can't be metabolized in the citric acid cycle due to the reduced quantity of acetate, which is used in gluconeogenesis, The body, instead, uses ketosis for energy, and ketogenesis results.

B. When carbohydrates are restricted, the body metabolizes fats for energy, resulting in a quantity of acetyl- CoA that can't be metabolized in the citric acid cycle due to the reduced quantity of oxaloacetate, which is used in gluconeogenesis, The body, instead, uses ketogenesis for energy, and ketosis results.

C. When carbohydrates are restricted, the body metabolizes proteins for energy, resulting in a quantity of acetyl-SCoA that can't be metabolized in the citric acid cycle due to the reduced quantity of oxaloacetate, which is used in gluconeogenesis, The body, instead, uses ketogenesis for energy, and ketosis results.

Answer 1

When Diets that severely restrict carbohydrate taken often result in ketosis for the diester.

because,

,When carbohydrates are restricted, the body metabolizes fats for energy, resulting in a quantity of acetyl- CoA that can't be metabolized in the citric acid cycle due to the reduced quantity of oxaloacetate, which is used in gluconeogenesis, The body, instead, uses ketogenesis for energy, and ketosis results.

1) Ketogenesis is the process of energy release in fatty acids.

2) Fatty acids are enzymatically broken down in β-oxidation to form acetyl-CoA.

3) Under normal conditions, acetyl-CoA is further oxidized by the citric acid cycle (TCA/Krebs cycle) and then by the mitochondrial electron transport chain to release energy.

4) Because of certain reason mainly due to low oxaloacetate intermedi TCA activity is low then ABNORMALY

Acetyl CoA is used in biosynthesis of ketone bodies via acetoacyl-CoA and β-hydroxy-β-methylglutaryl-CoA (HMG-CoA).

Answer option (B).

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