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In: Math

Advair, a combine bronchodilator and inhaled steroid is relatively slow working. Usually a patient has to...

Advair, a combine bronchodilator and inhaled steroid is relatively slow working. Usually a patient has to wait at least an hour before the full effect of this medicine kicks in. We were interested whether the patients could be reclassified (from severe to moderate COPD) within one-hour based on their Advair intervention. Measurements were made before the Advair was administered and then exactly one-hour after the treatment. Here are the data.

Advair Intervention - Test #2a

Before Treatment

After Treatment

Severe

Moderate

Total

Severe

253

600

853

Moderate

513

188

701

Total

766

788

1554

So over 1,500 patients were studied. Of the 1,554, 853 (or 55%) were classified as being severe COPD patients before the Advair intervention and then after the intervention, this number dropped to 766 (or 50%).

So it appears there was an effect within the one-hour time period. Now we need to show it statistically.

So using the McNemar test, test the claim at 95% confidence that there was an Advair intervention effect.

  1. State the Null and Alternative Hypotheses (1)
  2. State the Decision Rule (2)
  3. Determine the McNemar test statistic (3)

State your Decision and Interpretation. (1,1)

Solutions

Expert Solution

milcah answered 1 year ago
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