1. Why do men with prolactin-secreting tumors often present with more advance disease than do women?...

1. Why do men with prolactin-secreting tumors often present with more advance disease than do women? [5 marks]

2. What are the clinical features of excessive production of growth hormone in adults?

Expert Solution

1. The higher preoperative serum prolactin level and the immunoreactive tumor cells or MIB-1 index in males compare to women causes the increased frequency of the macroadenomas in the male. In males,the prolactin-secreting tumors produces the symptoms of the erectile dysfunction, loss of body and facial hair and increased size of breast in the advanced stage.In women, it can be noticed earlier when it is small because it causes the irregular menstruation, milky discharge from breast, excess facial and body hair growth, acne and the vaginal dryness.

2.Clinical features of the excessive production of growth hormones in adults -

The excessive production of growth hormones in adults causes the acromegaly disorder, the clinical features includes the enlargement of the face and hand, change in the shape of the face,enlargemnt of nose, thickening of lips and protruduction of the jaw bones. Additionally, it also includes the skin tags formation, erectile dysfunction in males,impaired vision,enlargement of the vocal cord and sinus, the enlargement of body internal organs, muscle weakness, restricted joint mobility, sexual irregularities.

Sydney Mullin answered 1 year ago

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