Question

1. If you have a gallstone, how can does this affect lipid absorption?

2.which blood vessel will be regulated using myogenic or tubuloglomerular feedback?

3.would increasing concentration of active osmotic material with blood and decreasing capillary permeability increase glomerular filtration rate?

4. if a kidney stone stops urine from flowing out of kidneys, what happens to filtration pressure?

5.if juxtaglomerular apparatus could not send signals which regulation would not work tubuloglomerular or myogenic?

Answer 1

1.The gallstones are the hardened materials formed from the bile and bilesalts.This stones blocks the bileduct and as a result the the bile cannot reach the duodenum.the bile is essential for the emulsification of fat and hence the lipid absorption takes a hit.The bile acids present in the bile are essential in the emulsification of the fat and converts them into micelles for absorption.Thus the gallstones prevent the lipid absorption by reducing micelle formation.

2.The afferent arteriole will be regulated via the myogenic or tubuloglomerular feedback.

The myogenic feedback

The myogenic mechanism works in the afferent arteriole that supplies the glomerulus. When blood pressure increases, smooth muscle cells in the wall of the arteriole are stretched and in response to this stretch they contract to resist the pressure. When blood pressure decreases, the smooth muscle wall relaxes and the resistance is lowered,and an even flow of blood occurs.

Tubuloglomerular feedback

This involves the JGA cells and paracrine signalling mechanism.They respond accordingly by either constricting or relaxing the afferent arteriole.