Question

Describe at least 3 different plasma proteins and their contributions to homeostasis by describing their production and function.

Answer 1

Plasma proteins are tge group of proteins that are present in thr plasma. The three main plasma proteins are albumin, globulin and fibrinogen.
Albumin is synthesised in the liver as pre proalbumin which is converted to proalbumin by action of peptidase. Proalbumin is then converted to albumin by furin. The albumin then enters the ECF.
Albumin binds to various proteins, hormones and ions and help in their transportation.
2. Globulin : globulin are another type of plasma proteins. Globulin are synthesised in the liver as well as lymphoid tissue. Globulin takes part in the body immune system and fights against infections.
3. Fibrinogen : fibrinogen is an another important plasma protein synthesised in liver and passed onto blood. During vasccular injury fibrinogen is converted to fibrin in the presence of thrombin. Fibrin is further converted to fibrin clot in the presence of blood cloting factor Xlll.
The plasma proteins take part in homeostasis. Albumin helps maintain the oncotic pressure in the capillaries and thus prevent leakage of fluid from blood. This helps maintain the normal blood volume in body.
Plasma protein also acts as a buffer system. During increased acidity of blood, plasma proteins binds to H+ ions thus reducing the blood acidity and increasing blood ph.
Fibrinogen takes part in clotting. During vascular injury fibrinogen is converted to fibrin which helps in clot formation and prevent excess blood loss from the body.