explain why burns pose a major threat to the body.

Solutions

Expert Solution

Before Going throught the pathophysiology of burns Lets look at anatomy of skin.

Skin is the largest organ of the body.
It has 3 major tissue layers.

Epidermis
The outermost layer, the epidermis, is composed of stratified epithelium.
The stratum corneum acts as a barrier to impede the entrance of microorganisms and toxic substances while allowing the body to retain water and electrolytes.

Dermis
Beneath the epidermis is the dermis, which is composed of a dense fibroelastic connective-tissue stroma containing collagen and elastic fibers and an extracellular matrix. The dermal layer contains an extensive vascular and nerve network, special glands, and appendages that communicate with the overlying epidermis.
it has two parts
a. Papillary dermis
b. Reticular dermis

Subcutaneous tissue -
The third layer of skin is subcutaneous tissue, which is composed primarily of areolar and fatty connective tissue

Pathophysiology of burns -

1. Burn causes heat coagulation necrosis of skin and subcutaneous tissue which releases vasoactive peptides

that causes alteration of capillary permeability, which causes loss of intravascular fluid and leads to Severe

hypovolemia.

2. Due to decreased myocardial fucntion cardiac output also decreases.

3. Decreased cardiac outflow and Poor circulation leads to decrease GFR which cause oliguria and Renal failure.

4. Loos of Skin barrier and decreased function of immune system leads to increased infection rate and Sepsis.

5. Shock - Tissue destruction results in increased capillary permeability with profound egress of fluid from the

intravascular space to the tissues adjacent to the burn wound. Inordinate amounts of fluid are lost by evaporation

from the damaged surface that is no longer able to retain water. This increase in capillary permeability, coupled with

evaporative water loss, causes hypovolemic shock.

Sydney Mullin answered 9 months ago

Next > < Previous

Related Solutions

Explain how/why data mining and web mining respectively pose a threat to both individual and group...

Explain how/why data mining and web mining respectively pose a threat to both individual and group privacy. Why does it matter? List at least three privacy-enhancement technologies (PETS) that exist to protect users and how/whether they work

1) Does increasing poverty and homelessness pose a threat to the broader economy? Why or why...

1) Does increasing poverty and homelessness pose a threat to the broader economy? Why or why not? 2) What, if anything, is the role of all levels of government(federal, state, and local governments) in reducing poverty and homelessness in the United States? Address poverty and homelessness from an economic point of view.

"explain why gloabl climate change is a major threat to biodiversity" PLEASE INCLUDE AS MUCH DETAIL...

"explain why gloabl climate change is a major threat to biodiversity" PLEASE INCLUDE AS MUCH DETAIL AS POSSIBLE

Do nontariff trade barriers pose a significant threat to free trade?

When looking at the threat landscape, there are different types adversaries and they pose different types...

When looking at the threat landscape, there are different types adversaries and they pose different types of threats depending on their capabilities, intentions, and the assets they are targeting. For example, nation states might target research companies or military websites trying to steal confidential and proprietary data. In addition, companies react to the loss of assets differently. The level and types of mitigation strategies will vary among organizations depending on whether there is a loss of one asset or of...

what short term and long term issues pose an immediate threat when establishing credit?

In “New Gene Tests Pose A Threat to Insurers” Pat Reilly had good reason to worry...

In “New Gene Tests Pose A Threat to Insurers” Pat Reilly had good reason to worry about Alzheimer’s disease: Her mother had it, and she saw firsthand the havoc it could wreak on a family, much of it financial. So Ms. Reilly, 77, a retired social worker in Ann Arbor, Mich., applied for a long-term care insurance policy. Wary of enrolling people at risk for dementia, the insurance company tested her memory three times before issuing the policy. But Ms....

Environmental pollution is a major threat for today's contemporary world. Explain the intervention measures available to...

Environmental pollution is a major threat for today's contemporary world. Explain the intervention measures available to limit externalities by a country. Mention at least one example for each measure.

how is climate change a major threat to biodiversiry

What kinds of technology pose the greatest threat ( automated robotics, super computers, cyborgs, androids)? answer...

What kinds of technology pose the greatest threat ( automated robotics, super computers, cyborgs, androids)? answer with examples please

Subjects