List the steps of the sliding filament model

Expert Solution

Sliding filament theory explain how a skeletal muscle is contracted when it is stimulated

The following are the main steps in the sliding filament theory

1) moto nerve supplying the msucle releases Acetylcholine neurotransmitter into the synaptic cleft of the neuromuscular junction

2)Acetylcholine moves through tyhe cleft to the post synaptic receptor present in the motor endplate and bind with the receptor producing action potential in the cell

3)action potential travel along the T tubule and result in the release of calcium ion into teh sarcoplasm from the sarcoplasmic reticulum.

4)calcium ion bind with the troponin present on the tropomyosin filament causes rotation of the tropomyosin over the actin filament resulting in the exposure of the Actin binding site

5)Myosin will bind with the actin on the actin binding site with the help of ATP and produce sliding of actin filament over the myosin filament (power stroke ) .sarcomere are contracted.The thin filament are overlapped over the thick filament forms the A band (anisotropic band) and the central zone called H zone is disappeared.

6)when the action potential is not stimulating the motor endplate , the release f the calcium ion from the sarcoplasmic reticulum will stops.

7) The troponin-tropomyosin are configured to the normal position covering the actin binding site

8)Muscle relaxes.

6)

Sydney Mullin answered 9 months ago

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