Skeletal muscle: aspects of substrate utilization by activity, muscle type, activation

Solutions

Expert Solution

Tthe main substrate utilized by the Skeletal muscles are Carbohydrate like glucose, Fattyacid from the lipid, Lactic acid.

The substrate utilization by the skeltal muscle will depend upon the condition.

If there is enough oxygen supply to the skeletal muscle, it will utilize the glucose for ATP production by means of cellular Respiraton.

If there is no glucose available, the body will depend Mainly on the Fats.

Fat are digested into Fattyacid and Glycerol.

Fatty acid are further oxidised to Acetyl coA by Beta oxidation ,Acetyl coA enters the krebs cycle for ATP, NADH,FADH2 production.

NADH,FADH2 are further trasnported to Electron transport chain for producing ATP.

When skeletal muscle is defficient of Oxygen supply , Pyruvic acid formed as a part of Glycolysis will enter the Lactic acid fermentation reaction in which pyruvic acid is converted into lactic acid . it will produce NAD+ which are utilised for the Glycolysis and ATP are generated.

2)Skeletal muscle is a striated muscle.

Long cylindrical muscle

multinucleated cell

Volundary muscle innervated by the somatic nervous system.

function : Movement of the body

3) when a motor nerve innervate the the muscle fibre(myofibrils) , pre synaptic nerve endings releases acetylcholine neurotransmitter into the synapse -------> it bind with the postsynaptic receptor on the muscle membrane -------> depolarises the sarcolemma(muscle membrane) ------->depolarisation of the T tubules -------->Calcium ion are released by the sarcoplasmic reticulum into the sarcoplasm------> it bind with the Troponin c present on the tropomyosin - actin complex------> change in spatial configuration of the tropomyosin result in the exposure of actin binding site -------> Myosin filament bind with the exposed actin binding site ----> Actin filament(thin) slide over the myosin(thick) filament ----> muscle contract.

Sydney Mullin answered 11 months ago

Next > < Previous

Related Solutions

Skeletal Muscle System Muscle Contraction The phase of the sliding filament mechanisms are activation of myosin...

Skeletal Muscle System Muscle Contraction The phase of the sliding filament mechanisms are activation of myosin followed by __________; the last step is _______. The detachment phase requires ___________. The power stroke phase requires __________. A crossbridge is formed between _________. Calcium binds to ________ which is necessary for _________. At the neuromuscular junction, __________ is released by the neuron; it binds to ________ on the muscle cell to eventually trigger ___________. Action potentials in skeletal muscle cells are needed...

During static muscle activity, there is a strong compressive effect from skeletal muscle contraction coupled with...

During static muscle activity, there is a strong compressive effect from skeletal muscle contraction coupled with an absence of rhythmic muscle activity. Describe how this would change arterial pressure (afterload) and venous return (preload) compared with dynamic activity.

how does the skeletal muscle produce ATP at different activity levels?

Skeletal muscle: changes that are possible to skeletal muscle and under what circumstances

Skeletal muscle fibers can be classified according to the predominant type of metabolism that the fiber...

Skeletal muscle fibers can be classified according to the predominant type of metabolism that the fiber relies on to produce energy needed for muscle contraction. List the 3 metabolic systems that skeletal muscle fibers rely on to produce energy for immediate use, short-term use, and longer-term use:

1. What is the function of skeletal muscle? 2. Describe the major components of skeletal muscle...

1. What is the function of skeletal muscle? 2. Describe the major components of skeletal muscle cels: Myofibrils Sarcomeres Motor unit Neuromuscular junction 3. How does skeletal muscle produce movement? 4. How do actin and myosin interact in a sarcomere to bring about muscle contraction? What roles do ATP and calcium play? 5. What is the functiion of the sarcoplasmic reticulum in muscle cell contraction? 6. Explain why calcium ions and ACh are vitals for muscle contraction. 7. What is...

As skeletal muscle temperature increases during exercise, what happens to the activity rate of the enzymes...

As skeletal muscle temperature increases during exercise, what happens to the activity rate of the enzymes involved in ATP resynthesis?

The contractile protein of skeletal muscle involving ATP ase activity is (a) troponin (b) tropomyosin (c)...

The contractile protein of skeletal muscle involving ATP ase activity is (a) troponin (b) tropomyosin (c) myosin (d) a-actinin

You are obviously still breathing during an anaerobic activity like sprinting. If the skeletal muscle cells...

You are obviously still breathing during an anaerobic activity like sprinting. If the skeletal muscle cells in your legs are performing lactic acid fermentation to produce the necessary ATP for their proper functioning, what is happening to the O2 gas you are breathing?

) Describe how skeletal muscle derives ATP over a period of prolonged activity. Use these subheadings as...

) Describe how skeletal muscle derives ATP over a period of prolonged activity. Use these subheadings as a guide to start your thinking. Do this out loud in lab and by hand later: Creatine Phosphate Oxidative Phosphorylation Glycolysis Glycogen Circulating Glucose Circulating Fatty Acids Amino Acids Lactic Acid High Oxygen Levels Low Oxygen Levels Gluconeogenesis

Subjects