In: Biology
Explain why NADPH is considered a reducing agent although the NADPH itself loses electrons.
NADPH molecules are created when a negative hydride anion is bonded to a molecule of NADP+. When this NADPH is used as reducing agent, each NADPH molecule gives up the hydride anion, by providing two electrons in order to move the reaction forward. In this process, a NADP+ molecule is also released.
When we take an example these reducing agents plays an important role in anabolism. For the formation of many of the molecules,your cells relies on NADPH as a reducing agent to help drive the needed oxidation-reduction reactions forward.
The above reaction is an example for how NADPH acts as reducing agent by losing its electrons. This is a reaction that creates a molecule of the fatty acid palmitate. As you can see, before the reaction there are 14 NADPH molecules and afterwards 14 NADP+ molecules are released by losing its hydrogen electron.