In: Chemistry
Explain how metal ions can form part of the structure of enzymes, and also how it can contribute to catalysis
Protiens were constituted with enzymes. And a enzyme further having two parts. First part apoenzyme which itself become inactive for biological activity. And second, coenzymes or cofactor, which is a nonprotein molecules having mrtal ion tthat is required for the protein's biological activity. Cofactor bind with the protein molecule (apoenzyme) to form the active enzyme (holoenzyme). These proteins are commonly enzymes, and cofactors can be considered "helper molecules" that assist in biochemical transformations.
Metalloenzymes with tightly bound metal ions to carry out a catalytic reaction. Metals often facilitate the catalytic process in different ways. The metals can either assist in the catalyic reaction, activate the enzyme to begin the catalysis or they can inhibit reactions in solution. Metals activate the enzyme by changing its shape but are not actually involved in the catalytic reaction.