Question

In: Biology

Consider the malate dehydrogenase reaction from the citric acid cycle. Given the listed concentrations, calculate the...

Consider the malate dehydrogenase reaction from the citric acid cycle. Given the listed concentrations, calculate the free energy change for this reaction at energy change for this reaction at 37.0 ∘C37.0 ∘C (310 K). Δ?∘′ΔG∘′ for the reaction is +29.7 kJ/mol+29.7 kJ/mol . Assume that the reaction occurs at pH 7.

[malate]=1.53 mM

[oxaloacetate]=0.240 mM

[NAD+]=310 mM

[NADH]=120 mM

Δ? = ____ kJ⋅mol−1

Solutions

Expert Solution

The Gibbs free energy of the reaction is 22.491 kJ/mol.

Explanation

*please give thumb up*


Related Solutions

Consider the malate dehydrogenase reaction from the citric acid cycle. Given the listed concentrations, calculate the...
Consider the malate dehydrogenase reaction from the citric acid cycle. Given the listed concentrations, calculate the free energy change for this reaction at energy change for this reaction at 37.0 ∘C37.0 ∘C (310 K). ΔG∘′ΔG∘′ for the reaction is +29.7 kJ/mol+29.7 kJ/mol . Assume that the reaction occurs at pH 7. [malate]=1.27 mM [oxaloacetate]=0.150 mM [NAD+]=150 mM [NADH]=6.0×101 mM ΔG:_______________kJ⋅mol−1
Consider the malate dehydrogenase reaction from the citric acid cycle. Given the following concentrations, calculate the...
Consider the malate dehydrogenase reaction from the citric acid cycle. Given the following concentrations, calculate the free energy change for this reaction at 37.0 �C (310 K). ?G�\' for the reaction is +29.7 kJ/mol. Assume that the reaction occurs at pH 7. [malate] = 1.35 mM [oxaloacetate] = 0.150 mM [NAD ] = 310 mM [NADH] = 120 mM
Consider the final reaction in the citric acid cycle, catalyzed by malate dehydrogenase: Malate + NAD+  ⇄...
Consider the final reaction in the citric acid cycle, catalyzed by malate dehydrogenase: Malate + NAD+  ⇄ oxaloacetate + NADH + H+ Equilibrium concentrations of the reaction components were measured as follows: [malate] = 5.28 mM [NAD+] = 75 uM [oxaloacetate] = 14.5 uM [NADH] = 14.5 uM pH = 8.83 a) From these data calculate the equilibrium constant, Keq, for this reaction. b) Calculate the standard free-energy change, ΔG°’, for this reaction (hint: remember that the prime means that the...
In the citric acid cycle, malate is oxidized to oxaloacetate by the enzyme malate dehydrogenase, which...
In the citric acid cycle, malate is oxidized to oxaloacetate by the enzyme malate dehydrogenase, which uses NAD+ as an electron acceptor. In cells, the ratio of [NAD+]/[NADH] is kept very high. Given the following standard reduction potentials, explain why it is so important for cells to maintain this ratio. Justify your answer with words, equations and diagrams. oxaloacetate + 2H+ + 2e- -> malate E°red= -0.166 V NAD+ + H+ + 2e- > NADH E°red= -0.320
3. The rate of the citric acid cycle is controlled by— A) a-ketoglutarate dehydrogenase. B) isocitrate...
3. The rate of the citric acid cycle is controlled by— A) a-ketoglutarate dehydrogenase. B) isocitrate dehydrogenase. C) citrate synthase. D) all of the above. E) none of the above
22. The pyruvate dehydrogenase complex provides a transition between glycolysis and the citric acid cycle. Which...
22. The pyruvate dehydrogenase complex provides a transition between glycolysis and the citric acid cycle. Which co-factors are considered stoichiometric and which are considered catalytic? 23. Which conditions exert a negative influence (reduce the activity) of pyruvate dehydrogenase? 24. What is the critical role for lipoic acid in the pyruvate dehydrogenase complex? 25. Central to the function of the citric acid cycle are two decarboxylation reactions. What are these decarboxylation reaction? 26. Your friend tells you of a celebrity touting...
Write with structural formulas and cofactors the reaction from the citric acid cycle, where a high...
Write with structural formulas and cofactors the reaction from the citric acid cycle, where a high energy thioester bond is broken.
inThe citric acid cycle there are three reactions of the citric acid cycle it's self that...
inThe citric acid cycle there are three reactions of the citric acid cycle it's self that are regulated: -citrate synthase which is where ATP inhibits in in citeo -isocitrate dehydrogenase: alosterrically activated by Ca2+ and ADP also is inhibited by NADH - alpha ketoglutarate dehydrogenase which is where Ca2+ increases the rate of formation of succinyl-CoA what would happen if all three of these reactions were not present? what would happen if citrate synthase was not functioning, what would happen...
1. Describe the reaction steps of the citric acid cycle with a focus on their control....
1. Describe the reaction steps of the citric acid cycle with a focus on their control. In addition discuss the energy provided to a living cell from the metabolism of one acetyl-CoA entering the citric acid cycle. biochemistry
Describe the reaction of the citric acid cycle and for each step explain the type of...
Describe the reaction of the citric acid cycle and for each step explain the type of reaction, enzyme involved, substrate and product, if the reaction is reversible or irreversible, any coenzyme or prosthetic group involved, and location.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT