Explain in detail the physiological functions and mechanisms of
action of a neurotransmitter (Acetylcholine) and explain...
Explain in detail the physiological functions and mechanisms of
action of a neurotransmitter (Acetylcholine) and explain how drugs
can alter their function.
Explain in detail the physiological functions and mechanisms of
action of a neurotransmitter (Dopamine) and
explain how drugs can alter their function.
Acetylcholinesterase catalyzes the hydrolysis of the
neurotransmitter acetylcholine: Acetylcholine + H2O acetate +
choline The Km of acetylcholinesterase for its substrate
acetylcholine is 9.5x10-5M. In a reaction mixture containing 5
nanomoles/mL of acetylcholinesterase and 150μM acetylcholine, a
velocity vo=40μmol/mLsec was observed for the acetylcholinesterase
reaction.
a. Calculate Vmax for this amount of enzyme
b. Calculate kcat for acetylcholinesterase
c. Calculate the catalytic efficiency (kcat/Km) for
acetylcholinesterase
d. Does acetylcholinesterase approach catalytic perfection?
e. What determines the ultimate speed limit...
explain the different effects the neurotransmitter acetylcholine
has on voluntary skeletal muscle versus cardiac muscle. for each
type of muscle, identify the subdivision of the nervous systerm
that is releasing acetycholine.
Answer the following:
Describe the mechanisms by which acetylcholine affects heart
rate.
Describe the mechanisms by which epinephrine affects heart
rate.
Describe the mechanisms by which atropine followed by
acetylcholine affects heart rate.
Epinephrine mimics the effects of which branch of the autonomic
nervous system?
Compare the effect of acetylcholine on cardiac muscle with its
effect on skeletal muscle. Can you explain the mechanistic basis
for the difference?
(from The ECG). Explain the physiological mechanisms that are
responsible for the variation in resting heart rate that occurs
during inspiration and expiration.
There are often several receptor subtypes for one
neurotransmitter, like acetylcholine, which are distributed in
different parts of the nervous system. Why might it be useful to
have different receptor subtypes in specific areas? What clinical
implications would it have?
For each of the five neurotransmitter systems dopamine,
norepinephrine, glutamate, GABA and acetylcholine list: their known
receptors, whether they are metabotropic or ionotropic and a
general function the system mediates
Explain in detail why you agree or disagree with affirmative action
and explain in detail how affirmative action will be affected by
the growing workforce diversity. (In your own words please
asap)