Please draw the reaction in which glutamate and oxaloacetate are converted to another amino acid and...

Please draw the reaction in which glutamate and oxaloacetate are converted to another amino acid and TCA intermediate. Draw the full reaction and label all reactants, enzymes, and products.

Solutions

Expert Solution

Asparate transaminase catalyzes the reversible transfer of the amino group from glutamate to oxaloacetate while repalcing the amino group of glutamate with a carbonyl group.

The reaction catalyzed by AST requires the cofactor known as pyridoxal-5-phospahte, the active form of vitamin B6. It binds covalently, but reversibly to an active-site lysine. this helps catalyze the reaction by accepting the amino group from the amino acid and the transferring it to the cabonyl compound.

queen_honey_blossom answered 1 year ago

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