Describe the two different disease manifestations of Varicella-Zoster virus.

Expert Solution

Disease manifestations of Varicella-Zoster virus :-

This is member of herpesvirus group and contains DNA as nucleic acid.

1. Varicella/ Chicken pox :-
• This is a highly infectious disease which is common in child age.
• It is characterized by vesicular rashes on trunk mainly.
• This infection spreads through respiratory route from diseased person to healthy person.
• One infection of this disease provides life long immunity.
• Infection in adults is more severe then children. This virus can also cross the placenta and may cause congenital anomalies.

2. Herpes zoster :-
• This is disease of old age and infects person who had chicken pox several years earlier.
• Virus remains in sensory ganglia for a long time and its infection is suppressed by immunity. But when immunity has fallen then this virus reactivated and causes neuritic pain and skin lesions.
• Mainly thoracic nerves are involved in this disease.

gladiator answered 2 years ago

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