Question

2) Those strange gamma/delta T cells differ from the more typical and common alpha/beta T cells in which ways (circle all that apply):

-They are the more common type of T cell receptor in adults

-They do not need the CD3 chains to interact with their TCRs

-They may occur earlier in fetal development than alpha/beta T cells

-They always express high levels of CD4 and CD8, even when mature

Answer 1

ANSWER:

correct answer -They do not need the CD3 chains to interact with their TCRs

Gamma/deltaT cells are activated in an MHC-independent manner, in striking contrast to MHC-restricted  alpha/beta T cells.They have  a prominent role in recognition of lipid antigens. They are of an invariant nature and may be triggered by heat shock proteins (HSP)  and activate adaptive immunity cells.

Explaination why other options are wrong

1. alpha/beta T cells are more common type of T cell receptor in adults (95%) and Gamma/deltaT cells constitue only 5%.
2. alpha/beta T cells occur earlier than gamma/deltaT cells because because they help in the positive selection of T cells and the T cells which do not intract with MHC undergoes apoptosis are recognised by gamma/deltaT cells for the process.
3. The do not need CD4/CD8 because they get activated in an MHC independent manner.

(Please like the answer if it is helpful for you thanks)