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what would happen if N. gonorrhoeae formed fimbriae with some epithelial cells lining the urethra? Sperm...

what would happen if N. gonorrhoeae formed fimbriae with some epithelial cells lining the urethra? Sperm cells?

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Expert Solution

Ans . If the N. gonorrhoeae formed fimbriae with some epithelial cells lining the urethra , then the epithelial cell invasion occurs .

The cells are invaded while they are still attached to the epithelial lining of urethra.The ability of N. gonorrhoea to invade urethral squamous epithelial cells would also provide a protected environment.

The infection occurs in four stages :-

The first stage represents attachment and fusion of plasma membrane with the bacterial membrane .

This is followed by second stage , uptake of the organisms by the epithelial cells and incorporation into vacuoles.

In the third stage of infection , the N.gonorrhoea appears to replicate within the vacuoles .

In the fourth stage , organisms rupture from the cells into the urethral lumen , and infected epithelial cells are shed. These released organisms reinfect other epithelial cells.


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