16. (short answer) Hypothesize what would happen if thyroid cells could not respond to TSH. Suppose...

16. (short answer) Hypothesize what would happen if thyroid cells could not respond to TSH. Suppose a doctor did a blood draw. Would the levels of TSH be high or low? Thyroid hormone? TRH?

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Expert Solution

ANSWER 16 :-

Null Hypothesis :- There is no statistically significant relationship between the improper functioning of the thyroid gland (thyroid cells) and the Thyroid stimulating hormone.

Alternate Hypothesis :- There is a statistically significant relationship between the improper functioning of the thyroid gland and the Thyroid Stimulating hormone.

The condition can be explained in short. When the thyroid stimulating hormone is not able to act on and stimulate the thyroid gland, it indicates a condition called as hypothyroidism in which there is relatively less production of the thyroid hormones namely T3 and T4 which plays a vital role in the process of body metabolism.
In this case, the levels of TSH obtained from the blood test will be elevated as compared to the levels of the thyroid hormones. This indicates that the negative feedback loop mediated by the thyroid hormones by means of preventing the interaction between the Thyroid Releasing hormone and the Pituitary gland which in turn prevents the release of the TSH. But here the case is reversed, there will be elevation in the levels of TSH taking into consideration that the negative feedback loop becomes non-functional and hence TSH levels will elevate in order to stimulate Thyroid gland to release thyroid hormones and thus this indicates that the levels of Thyroid hormones in the blood will be less and the levels of Thyroid Stimulating hormone and Thyroid releasing hormone in the blood will be high.

gladiator answered 1 week ago

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