In: Anatomy and Physiology
distinguish structurally and functionally between primordial follicles, primary follicles, secondary follicles and a mature follicle.
Primordial folicle
Ovary contain 4,00,000 primordial folicle at time of puberty. It is 15 micron in diameter and each one has an ovum in it . It is surrounded by the granulosa cells in our body .
it helps in maturation of the ovum and granulosa cells in it helps in nutrition of the ovum . They secrets occyte maturation inhibitor factor .
Primary folicle
It is formed when the ovum is completely surrounded with granulosa cells without space . In this stage folicle increase in size up to 30 microns and ovum increase size up to 21 microns . Connective tissue fines around folicle
They help in the growth and protection of ovum
Secondary follicle
Under influence of Folicle stimulating hormone they develop into secondary folicle.
Changes taking place are
1) granulosa cells change that is antrum is formed between cells. And proliferation of granulosa cells occur . Ovum is pushed to one side of the granulosa cells
2). Ovum size change become 100 microns and cytoplasm become granular
3) capsule is formed and follicular sheath is formed and is divided into theca interna and externa
They have vascular smooth tissue and blood supply is higher. Epithelial cells of theca interna secrete estrogen and hormones jnti antrum
At 7 th day of menstural cycle the vesicular folice become dominat folicle
Mature folicle
Structure
It extent through all thickening of ovarian cortex . Folicle cavity become larger and distended. Zona pellucida become thicek and Corona radiata become thick .
Function
It is the corpus luteum that is formed after the ovulation process
It secretion are progesterone that will help in presidency of pregnancy and is evident .
After ovulation they become corpus hemorrhagicm and is converted to corpus luteum and if fertilization occur the corpus luteum of pregnancy and if fertilization does not occur then corpus luteum menstrualis