Briefly describe the role of ACh in the Peripheral and Central Nervous Systems (150 words)

Expert Solution

Role of acetylcholine (ACh) in peripheral and central nervous systems:

Acetylcholine (ACh) is an organic chemical which helps in the functioning of brain and body by acting as a neurotransmitter.

Its role in peripheral nervous system:

In the peripheral nervous system, acetylcholine (ACh) causes the contraction of skeletal muscles.
It also plays an important role in the signaling of movement of muscles, learning and formation of memory, sensation of pain, regulating endocrine system and also in the movement of eyes.
It activates muscles and also regulates rapid eye movement (REM) sleep cycle.

Its role in central nervous system:

In the central nervous system (CNS), acetylcholine (ACh) acts by inhibiting the action of cholinergic system for transmitting nerve impulses.
It causes the contraction of muscles and activates the pain responses.
It helps in the functioning of passing cholinergic projections from the basal forebrain to the cerebral cortex.
The main role of acetylcholine in central nervous system is excitatory and it also plays role in memory, neuroplasticity and learning.

Thank you!

Sydney Mullin answered 1 year ago

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