endocrine function of the kidney

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Expert Solution

There are 3 important hormones produced by kidney

1. Renin

It is released from JG cells in response to decrease in GFR
It activates Renin angiotensin aldosterone system.

2. Erythropoietin

It is released in response to decrease in Oxygen saturation of blood.
It leads to maturation of erythroblast precursor cells and increases production of erythrocytes (red blood cells)

3. Calcitriol

It is active form of vitamin D and it is considered as hormone.
Vitamin D is first activated in liver where it is hydroxylated at 25' to form 25' hydroxyvutamin D then in kidney at 1' position to form 1,25 dihydroxyvitamin D3 (or Calcitriol) which is active form.
Calcitriol then act and increase Blood calcium level by increasing its absorption from GIT.

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Sydney Mullin answered 11 months ago

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