50 units of protein A are required per cell to establish a wild-type phenotype. A single...

50 units of protein A are required per cell to establish a wild-type phenotype. A single wild-type allele of gene A produces 40 units of enzyme per cell. Which of the following statements is true regarding the wild type allele. Select ALL that apply.

		They are haplosufficient
		They are haploinsufficient
		They are recessive to null alleles
		They are dominant to hypomorphs making less than 10 units of enzyme per cell.
		They are recessive
		They are recessive to hypomorphs making less than 10 units of enzyme per cell.

Solutions

Expert Solution

	1. They are haplosufficient The allele in haploid condition is not able to express phenotype so they are not haplosufficient
	2. They are haploinsufficient The allele in haploid condition is not able to express phenotype so they are haplo-insufficient
	3. They are recessive to null alleles Being recessive an allele is not able to express when heterozygous but they are expressing when in single active allele is there. So they are not recessive instead dominant.
	4. They are dominant to hypomorphs making less than 10 units of enzyme per cell. The above condition seems to be appropriate as discussed earlier it’s a dominant allele but other type of allele has not been discussed in the query so the statement here is quite suitable that it is dominant over allele with 10 units of enzyme production capability per cell
	5. They are recessive Being recessive an allele is not able to express when heterozygous but they are expressing when in single active allele is there. So they are not recessive instead dominant.
	6. They are recessive to hypomorphs making less than 10 units of enzyme per cell. Being recessive an allele is not able to express when heterozygous but they are expressing when in single active allele is there. So they are not recessive instead dominant.

gladiator answered 1 year ago

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