Question

In: Anatomy and Physiology

1. why can't A+ donate to A-? 2. why can A- donate to A+? 3. why...

1. why can't A+ donate to A-?

2. why can A- donate to A+?

3. why can't O+ donate to B-?

4. why can't B+ donate to AB-?

Solutions

Expert Solution

RBC's have antigens on their surface that serve as markers and plasma contains antibodies that detect and reject blood cells with foreign antigen.

1. In A- Blood group person A antigen present in the RBC ,no Rh antigen in RBC, but Rh Antibody present in there Plasma .A+ Blood have Both antigen A and Rh in RBC which induces the antigen antibody response in coming contact with A- Blood..Thus A+ can not donate the A-.

2.In A- Blood Antigen A is present ,Rh antigen is absent ,and in A+ Blood have Both antigen A and Rh in RBC ,but no antibody for Rh .Here no Rh incompatibility reaction occur.so we can not transfuse the A- blood in A+ person.

3.O+ Blood have antigen Rh present in the RBC but B- no Rh antigen but have Rh antibody present in the Plasma thus causes Rh incompatibility reaction ,so we can not transfuse the O+ blood in B- person.

4.B+ have antigen B and Rh antigen ,and AB- have both antigen A and B but dont have Rh antigen ,it contain antibody for Rh ,thus it induced Rh incompatibility ,so we can not transfuse the B+ blood in AB- person.


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