2. Describe the subcellular scheme by which a transmembrane cell surface receptor protein such as the...

2. Describe the subcellular scheme by which a transmembrane cell surface receptor protein such as the platelet derived growth factor receptor gets synthesized and placed at the cell surface. Start with a gene (DNA) but focus primarily on cellular endomembrane systems.

Expert Solution

GENE IS TRANSCIBED IN NUCLEUS mRNA IS TRANSPORTED TO CYTOPLASM HERE IN CYTOPLASM IT ATTACHES WITH RIBOSOMES AND TRASLATED WITH THE HELP OF tRNA. RIBOSOMES ATTACHED ARE FREE OR IN ATTACHMENT WITH ENDOPLASMIC RETICULUM i.e. ER A MEMBRANE BOUND ORGANELLE (SUCH ER WITH RIBOSOME ATTACHED ARE CALLED ROUGH ER). SO PROTEIN FORMED ENTERS THE RER AND FORMS VESICLES OF PROTEIN THROUGH ITS SMOOTH ER. VESICLE IS ALSO A MEMEBRANE BOUND ORGANELLE AS BULB COMING OUT OF SMOOTH ER AND BASED ON ITS RANDOM MOVEMENT OR ITS AFFINITY IT MERGE WITH THE CELL MEMBRANE. PROTEIN INSIDE THE VESICLE EMBEDS ITSELF AS TRANSMEMBRANE OR INTERIOR OR EXTERIOR OF MEMBRANE BASED ON THE THERMODYNAMIC STABILITY OF PROTEIN OR AFFINITY OF PROTEIN WITH OTHER MOLECULES (MAY BE OTHER PROTEIN OR ANY 3 D STRUCTURE)

gladiator answered 2 years ago

Describe 3 ways to determine whether a protein is a transmembrane or peripheral protein.

synthesis and transport of cell surface protein

Explain the different steps leading a 7 pass transmembrane receptor protein being exposed on the plasma...

Explain the different steps leading a 7 pass transmembrane receptor protein being exposed on the plasma membrane. You will start as the mRNA encoding for this protein was just exported outside of the nucleus.

Explain the different steps leading a 7 pass transmembrane receptor protein being exposed on the plasma...

Explain the different steps leading a 7 pass transmembrane receptor protein being exposed on the plasma membrane. You will start as the mRNA encoding for this protein was just exported outside of the nucleus.

structure and function of G-protein coupled receptors: binding of neurotransmitter/ hormone to 7-transmembrane receptor, activation of...

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2. (3pts) You are studying a single-pass transmembrane protein which is destined to the plasma membrane....

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trace the steps of a long and indirect signaling pathway from a cell-surface receptor to a...

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Explain the cell signaling pathway which involves membrane receptor (tyrosine kinase receptors and G protein-coupled receptors)....

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QUESTION 1 Which of the following is an enzyme? a G protein a G protein-coupled receptor...

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2. Describe the subcellular scheme by which a transmembrane cell surface receptor protein such as the...

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Describe 3 ways to determine whether a protein is a transmembrane or peripheral protein.

synthesis and transport of cell surface protein

Explain the different steps leading a 7 pass transmembrane receptor protein being exposed on the plasma...

Explain the different steps leading a 7 pass transmembrane receptor protein being exposed on the plasma...

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