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In: Anatomy and Physiology

Describe how the hypothalamus regulates the function of the anterior and posterior pituitary differently. (Answer using...

Describe how the hypothalamus regulates the function of the anterior and posterior pituitary differently. (Answer using complete sentences format only)

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Anterior pituitary gland :

  • Hypothalamus releases regulatory hormones (releasing and inhibiting hormones) that targets anterior pituitary gland and control its secretions.
    Example : TRH (Thyrotropin releasing hormone) from hypothalamus stimulates anterior pituitary gland to release TSH (Thyroid stimulating hormone).
  • The hypothalamus and anterior pituitary gland connects via two capillary beds called hypothalamic–hypophysial portal system that facilitates transport of hypothalamic hormones to anterior pituitary gland.



Posterior pituitary gland :

  • Hypothalamus and posterior pituitary gland are directly connected via hypothalamo-hypophyseal tract.
  • It is a nerve tract having cell bodies in the hypothalamus and nerve endings in the posterior pituitary gland.
  • This nerve tract passes through the pituitary stalk or infundibulum.
  • Hypothalamus produced two hormones : Oxytocin and Anti-diuretic hormone that are stored in nerve endings located in the posterior pituitary gland.
  • Upon stimulation, nerve impulse travel down the tract releasing these hormones from its secretory granules.
    Example : Osmoreceptos in hypothalamus sense increase fluid osmolarity. They stimulate posterior pituitary gland to release anti-diuretic hormone to conserve water and maintain homeostasis.

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