Question

Why do you think that the intestines have one of the body’s most well-developed sets of lymphoid tissues?

Answer 1

Intestinal lymphoid tissue-

The gut-associated lymphoid tissue (GALT) consists of organized lymphoid tissues, such as mesenteric lymph node (MLN) and Peyer's patches (PPs), and more diffusely scattered lymphocytes in the intestinal LP(lamina propria) and epithelium.

Lymphatic tissue is rich in lymphocytes (and accessory cells such as macrophages and reticular cells).

Why GALT most well-developed set of lymphoid tissue-

Explanation:-

Gut-associated lymphoid tissue is comprised of Peyer's patches, interdigitating lymphocytes, plasma cells and lymphocytes present in the lamina propria, and mesenteric lymph nodes. The role of GALT is to manage the immune response to the massive antigen exposure experienced by the gut while maintaining a potent adaptive immune response to protect the host from mucosal pathogens.

The mucosal epithelium of the gastrointestinal tract is deluged by potential pathogens on a continuous basis. Salivary enzymes, gastric acidity and surface mucous production provide a powerful barrier protection sufficient to protect against numerous invaders. However, an adaptive immune response is necessary to fully protect organisms against all virulent microbes. In the gut, a nework of interdigitating lymphocytes in the epithelium, in addition to lymphocytes and plasma cells that circulate through the lamina propria, play an imprtant role in dealing with ingested...