Why is reaction reversibility significant in DNA polymerization?

Expert Solution

DNA Polymerisation or DNA replication is process of molecular biology in which 2 replicas of DNA are produced from the parent or original DNA with the help of various enzymes and proteins.

For this DNA has to be healthy, but by some metabolic activities or environmental factors such as UV rays, cells of an organism gets damage in turn causes damage to the DNA in it.

DNA damage can be a fundamental problem for life. DNA damage can occur because of single or double strand breaks, by various types of modifications in bases and inter-strand crosslinks but is distinct from mutations.

these damages may block process of replication which can lead to the death of cell. If template strand having damage site gets replicated, it may pass inappropriate damaged information. This can also lead to cancer.

DNA repair is very important before DNA replicates. DNA reverses or repairs by five major pathways of which some are base excision repair, homologous recombinational repair, misatch repair etc.

Therefore, DNA repair is very significant in DNA polymerisation.

queen_honey_blossom answered 2 years ago

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