In: Biology
Calculate ?Go for the oxidation of NADH by FAD. Why is this reaction significant? Where used in metabolic processes? Eo’ = -0.219 V for FAD (electron acceptor) and –0.315 V for NADH (electron donor)
Ans.
Importance: The cell has a limited pool of NAD+, which is used as cofactor by some enzymes of the glycolysis as well as TCA cycle, and many more pathways. So, oxidation of NADH by FAD regenerate and replenish the NAD+ availability to various enzymes in the cell.