Question

Based on your knowledge of metabolism, describe why eating a fat free but high calorie diet can lead to fat gain. Describe the specific pathways that sugar can take to become stored lipids. No diagrams

Answer 1

Normally,Our body uses Glucose(Carbohydrates)for energy.

So After a meal, carbohydrates are broken down immediately into glucose as a source of energy.

But Excess glucose gets stored as glycogen in the liver or can be converted into fatty acids.

Glucose in Glycolysis-----------------Pyruvate.(1 Glucose-------------2 Pyruvate)

Pyruvate----------------------------------Acetyl coA (Pyruvate Decarboxylation by pyruvate dehydrogenase complex.)

[Pyruvate loses CO2 molecules to from Acetyl CoA in presence of pyruvate dehydrogenase complex)

From This Acetyl CoA,Fatty Acids are produced.

Acetyl CoA----------------------------Fatty Acids (Fatty acid Synthesis by Action of Fatty acid synthases)

This Fatty acids can be circulated to other parts of the body or stored as fat in adipose tissue. When there is overabundance of fatty acids------------ fat accumulates in the liver-----------Fatty Liver.

So by this way.....overconsumption of Carbohydrate more than required for Energy Consumption can lead to Fat gain even in absence of fat in the Diet