In: Statistics and Probability
In a test of the effectiveness of garlic for lowering cholesterol, 50 subjects were treated with garlic in a processed tablet form. Cholesterol levels were measured before and after the treatment. The changes (beforeminusafter) in their levels of LDL cholesterol (in mg/dL) have a mean of 3.7 and a standard deviation of 16.6. Construct a 99% confidence interval estimate of the mean net change in LDL cholesterol after the garlic treatment. What does the confidence interval suggest about the effectiveness of garlic in reducing LDL cholesterol? What is the confidence interval estimate of the population mean mu?
Solution:
Given that,
= 3.7 ....... Sample mean
s = 16.6 ........Sample standard deviation
n = 50 ....... Sample size
Note that, Population standard deviation() is unknown..So we use t distribution.
Our aim is to construct 99% confidence interval.
c = 0.99
= 1 - c = 1 - 0.99 = 0.01
/2 = 0.01 2 = 0.005
Also, d.f = n - 1 = 50 - 1 = 49
= = 0.005,49 = 2.680
( use t table or t calculator to find this value..)
The margin of error is given by
E = /2,d.f. * ( / n )
= 2.680 * (16.6 / 50 )
= 6.29
Now , confidence interval for mean() is given by:
( - E ) < < ( + E)
(3.7 - 6.29) < < (3.7 + 6.29)
-2.59 < < 9.99
Required interval is (-2.59 , 9.99)