Question

During activation of the sympathetic nervous system some body functions are excited while others are inhibited. Describe biochemical mechanisms by which this is possible

Answer 1

Answer:The sympathetic nervous system is a major effector of thermoregulatory responses. Downstream of DMH and raphe pallidus neurons, the sympathetic nervous system controls both nonshivering thermogenesis of the BAT and cutaneous thermoregulatory responses. Most of the  studies have detected sympathetic abnormalities in ALS patients. First, degeneration of autonomic nerve fibers, correlating with disease progression, is observed in skin biopsies . Second, multiple physiologic responses dependent upon the sympathetic nervous system are altered in ALS patients. These alterations include a prolonged sympathetic skin response, mainly in the lower extremities , increased muscle sympathetic nerve activity , increased resting heart rate, increased resting blood pressure.

Biochemical process: