Question

In: Chemistry

18. A transition-state analog: a. is less stable when binding to an enzyme than the normal...

18. A transition-state analog:
a. is less stable when binding to an enzyme than the normal substrate.
b. resembles the active site of general acid-base enzymes.
c. resembles the transition-state structure of the normal enzyme-substrate complex
d. stabilizes the transition state for the normal enzyme-substrate complex.
e. typically reacts more rapidly with an enzyme than the normal substrate.

12. Antibodies are used for the following purposes (circle all that apply):
a. to specifically labeling proteins in electrophoresis assays
b. as catalysts
c. as FDA-approved drugs
d. as a dessert topping
e. for protein purification

Solutions

Expert Solution

18. A transition-state analog:

Answer : (c) resembles the transition-state structure of the normal enzyme-substrate complex.

12. Antibodies are used for the following purposes:


Answer : (a) to specifically labeling proteins in electrophoresis assays.

b. as catalysts

c. as FDA-approved drugs

e. for protein purification

Antibodies are used in a test, or assay, called the enzyme -linked immunosorbent assay (ELISA), used in the home pregnancy test, which detects the presence of human chorionic gonadotropin (HCG), produced by human embryos.

Catalytic antibodies. Antibodies can be used to enhance the chemical reactivity of molecules to which they bind.


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