Question

In: Anatomy and Physiology

26) A. At many synapses in the hippocampus, long‑term potentiation depends on the             activation of...

26) A. At many synapses in the hippocampus, long‑term potentiation depends on the             activation of NMDA receptors which have affinities for and respond to __________:             

a. GABA.

b. glutamate.

c. dopamine.

d. norepinephrine.

e. nitric oxide.

B. Based on imaging research of the brain, the region known as DLPFC (dorsolateral    prefrontal cortex) is associated with __________:

            a. verbal tasks.

            b. executive control.

            c. spatial tasks.

            d. all of the above.

            e. none of the above.   

C. Tricyclic antidepressants, and some herbal remedies such as St. John's Wort, might share a    common mechanism, probably involving __________:

            a. blocking the release of glutamate and GABA.

            b. preventing the Presynaptic cell from reabsorbing monoamine neurotransmitters.

            c. directly stimulating catecholamine receptors in the post synaptic membrane.

            d. increasing the rate of synthesis of acetylcholine and ADP, and GDP. glutamate.

Solutions

Expert Solution

A.) Answer :- option b Glutamate


The NMDA receptor is a cation channel, but it permits passage of relatively large amounts of Ca"+2. . Firstly, glycine facilitates its function by binding to it.and glycine appears to be essenial for its response to glutamate.

B.)option b executive control

This option is correct becoz the dorsolateral prefrontal cortex allows people to create and execute plans. This region also helps individuals organize actions in a certain sequence, such as when a person needs to follow a recipe. Injuries to this region can interfere with people’s abilities to switch between tasks, recall where an instruction came from, or adapt to changes in rules.

C.)Answer

b. preventing the Presynaptic cell from

reabsorbing monoamine neurotransmitters.

This is because due to it inhibits reuptake of noradernaline and serotonin into the neuron .due to to which there is no decrease concentration of these monoamines in the synaptic cleft.


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