Dietary and lifestyle changes reduce the incidence of chronic
disease. Avoidance of smoking by preventing initiation or by
cessation for those who already smoke is the single most important
way to prevent CVD. Obesity is increasing rapidly worldwide
(chapter 45). Even though obesity—a body mass index (BMI) of 30 or
greater—has received more attention than overweight, overweight
(BMI of 25 to 30) is typically even more prevalent and also confers
elevated risks of many diseases. For example, overweight people
experience a two- to threefold elevation in the risks of CAD and
hypertension,
Medical experts have long recognized the effects of diet on the
risk of CVD, but the relationship between diet and many other
conditions, including specific cancers, diabetes, cataracts,
macular degeneration, cholelithiasis, renal stones, dental disease,
and birth defects, have been documented more recently.
- Replace saturated and trans fats with unsaturated fats,
including sources of omega-3 fatty acids. Replacing saturated fats
with unsaturated fats will reduce the risk of CAD (F. B. Hu and
Willett 2002; Institute of Medicine 2002; WHO and FAO 2003) by
reducing serum low-density lipoprotein (LDL) cholesterol. Also,
polyunsaturated fats (including the long-chain omega-3 fish oils
and probably alpha-linoleic acid, the primary plant omega-3 fatty
acid) can prevent ventricular arrhythmias and thereby reduce fatal
CAD. In a case-control study in Costa Rica, where fish intake was
extremely low, the risk of myocardial infarction was 80 percent
lower in those with the highest alpha-linoleic acid intake (Baylin
and others 2003). Intakes of omega-3 fatty acids are suboptimal in
many populations, particularly if fish intake is low and the
primary oils consumed are low in omega-3 fatty acids (for example,
partially hydrogenated soybean, corn, sunflower, or palm oil).
These findings have major implications because changes in the type
of oil used for food preparation are often quite feasible and not
expensive.
- Ensure generous consumption of fruits and vegetables and
adequate folic acid intake. Strong evidence indicates that
high intakes of fruits and vegetables will reduce the risk of CAD
and stroke (Conlin 1999). Some of this benefit is mediated by
higher intakes of potassium, but folic acid probably also plays a
role (F. B. Hu and Willett 2002). Supplementation with folic acid
reduces the risk of neural tube defect pregnancies. Substantial
evidence also suggests that low folic acid intake is associated
with greater risk of the colon—and possibly breast—cancer and that
use of multiple vitamins containing folic acid reduces the risk of
these cancers (Giovannucci 2002). Findings relating folic acid
intake to CVD and some cancers have major implications for many
parts of the developing world. In many areas, consumption of fruits
and vegetables is low. For example, in northern China,
approximately half the adult population is deficient in folic
acid.
- Consume cereal products in their whole-grain, high-fibre
form. Consuming grains in a whole-grain, high-fibre form has
double benefits. First, consumption of fiber from cereal products
has consistently been associated with lower risks of CAD and type 2
diabetes (F. B. Hu, van Dam, and Liu 2001; F. B. Hu and Willett
2002), which may be because of both the fiber itself and the
vitamins and minerals naturally present in whole grains. High
consumption of refined starches exacerbates the metabolic syndrome
and is associated with higher risks of CAD (F. B. Hu and Willett
2002) and type 2 diabetes (F. B. Hu, van Dam, and Liu 2001).
Second, higher consumption of dietary fibre also appears to
facilitate weight control (Swinburn and others 2004) and helps
prevent constipation.
- Limit consumption of sugar and sugar-based beverages.
Sugar (free sugars refined from sugarcane or sugar beets and
high-fructose corn sweeteners) has no nutritional value except for
calories and, thus, has negative health implications for those at
risk of overweight. Furthermore, sugar contributes to the dietary
glycemic load, which exacerbates the metabolic syndrome and is
related to the risk of diabetes and CAD (F. B. Hu, van Dam, and Liu
2001; F. B. Hu and Willett 2002; Schulze and others 2004). WHO has
suggested an upper limit of 10 percent of energy from sugar, but
lower intakes are usually desirable because of the adverse
metabolic effects and empty calories.
- Limit excessive caloric intake from any source. Given
the importance of obesity and overweight in the causation of many
chronic diseases, avoiding excessive consumption of energy from any
source is fundamentally important. Because calories consumed as
beverages are less well-regulated than calories from solid food,
limiting the consumption of sugar-sweetened beverages is
particularly important.
- Limit sodium intake. The principle justification for
limiting sodium is its effect on blood pressure, a major risk
factor for stroke and coronary disease (chapter 33). WHO has
suggested an upper limit of 1.7 grams of sodium per day (5 grams of
salt per day) (WHO and FAO 2003).