please explain the Fischer Esterification and mechanism of the Fischer Esterification concretely in your words!!!! Then...

please explain the Fischer Esterification and mechanism of the Fischer Esterification concretely in your words!!!!

Then explain why 1H-NMR is used to determine the unknown!!

Solutions

Expert Solution

Above is an example of esterification reaction . Reactants are acetic acid and butanol.In the first step of the reaction the O atom of C=O will be protonated followed by development of a positive charge on carbonyl carbon atom. As the -OH group of butanol contains lone pair of electron, they are able to act as a nucleophile and attacks the Positively charged center. Then a radid proton transfer occur to form a -OH2+ group whichhas good leaving group ability. It leaves the reaction center . Then a double bond is formed at the reaction center to give the product ester.

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1-H NMR can identify the unknown as it has greater number of protons that the reactants. Also, parent alcohol and acid will have completely different 1-H NMR pattern

queen_honey_blossom answered 1 year ago

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