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In: Anatomy and Physiology

It has been demonstrated that some people treated with statins show an increased accumulation of lipids...

It has been demonstrated that some people treated with statins show an increased accumulation of lipids in the liver and skeletal muscles, as well as a mitochondrial dysfunction in skeletal muscles. Explain why statin treatment results in lipid accumulation in the liver and in the skeletal muscle.

What other metabolite accumulates explaining why there is increased fatty acid synthesis if HMG-CoA (due to statin treatment) accumulates in the cytosol and slows downs the cholesterol synthesis pathway.

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Sydney Mullin answered 1 year ago
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