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In: Biology

Applying your knowledge of metabolism, glycolysis starts with one molecule of glucose (6C) and produces a...

Applying your knowledge of metabolism, glycolysis starts with one molecule of glucose (6C) and produces a net total of __________.

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Applying your knowledge of metabolism, glycolysis starts with one molecule of glucose (6C) and produces a net total of __________.

1) one pyruvates; 2 NADH; 2 ATP
2) one pyruvate; 2 NADH; 4 ATP
3) two pyruvates; 4 NADH; 2 ATP
4) two pyruvates; 2 NADH; 2 ATP   

Solutions

Expert Solution

Answer is option (4) Glycolysis starts with one molecule of glucose (6C) and produces a net total of two pyruvates; 2 NADH; 2 ATP. This pathway was described by Embden, Meyerhof and Parnas. Hence, it is also called as Embden-Meyerhof pathway. It is an extramitochondrial (cytoplasm) pathway and is carried by a group of eleven enzymes. can be divided into two phases:

Preparatory Phase :

This phase is also called glucose activation phase. In this phase of, two molecules of ATP are used and the glucose is cleaved into two triose phosphates glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. In this process, phosphorylation of glucose and it’s conversion to glyceraldehyde-3-phosphate take place. These step stogether are called as the preparatory phase.

Payoff Phase :

This phase is also called energy extraction phase. During this phase, conversion of glyceraldehyde-3-phophate to pyruvate and the coupled formation of ATP take place. Glucose is split to yield two molecules of D-Glyceraldehyde-3-phosphate, each step in the payoff phase occurs twice per molecule of glucose. These steps constitute payoff phase.


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