Question

Applying your knowledge of metabolism, glycolysis starts with one molecule of glucose (6C) and produces a net total of __________.

View Available Hint(s)

Applying your knowledge of metabolism, glycolysis starts with one molecule of glucose (6C) and produces a net total of __________.

1) one pyruvates; 2 NADH; 2 ATP

2) one pyruvate; 2 NADH; 4 ATP

3) two pyruvates; 4 NADH; 2 ATP

4) two pyruvates; 2 NADH; 2 ATP

Answer 1

Answer is option (4) Glycolysis starts with one molecule of glucose (6C) and produces a net total of two pyruvates; 2 NADH; 2 ATP. This pathway was described by Embden, Meyerhof and Parnas. Hence, it is also called as Embden-Meyerhof pathway. It is an extramitochondrial (cytoplasm) pathway and is carried by a group of eleven enzymes. can be divided into two phases:

Preparatory Phase :

This phase is also called glucose activation phase. In this phase of, two molecules of ATP are used and the glucose is cleaved into two triose phosphates glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. In this process, phosphorylation of glucose and it’s conversion to glyceraldehyde-3-phosphate take place. These step stogether are called as the preparatory phase.

Payoff Phase :

This phase is also called energy extraction phase. During this phase, conversion of glyceraldehyde-3-phophate to pyruvate and the coupled formation of ATP take place. Glucose is split to yield two molecules of D-Glyceraldehyde-3-phosphate, each step in the payoff phase occurs twice per molecule of glucose. These steps constitute payoff phase.