Explain why there can be no net glucose production from fatty acids and acetylCoA, although carbons...

Explain why there can be no net glucose production from fatty acids and acetylCoA, although carbons from acetylCoA can end up in glucose.

Expert Solution

In animals, metabolism of fatty acids doesn't directly give rise to lucose. Fatty acids are broken down two carbons at a time and they turn into acetyl units of acetyl coA. Now, there is no enzyme present that could conversation acetyl coA into any substance, like Pyruvate, that could enter the glucogenesis pathway that would result in the production of glucose. However, this acetyl coA enters Kreb's cycle that results in oxaloacetate. The oxaloacetate is on the glucogenesis pathway. However, OAA production is equal to OAA consumption and there is no net conversion of Acetyl coA into OAA. But some carbons of Acetyl coA are present in glucose.

queen_honey_blossom answered 2 years ago

explain why the carbons of even chain fatty acids can never be used to synthesize NET...

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An individual has an excess of glucose and converts the glucose into fatty acids for better...

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Every biochemistry student knows that most naturally occurring unsaturated fatty acids are "cis" fatty acids. Why...

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Explain why there can be no net glucose production from fatty acids and acetylCoA, although carbons...

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explain why the carbons of even chain fatty acids can never be used to synthesize NET...

1. Demonstrate the energy production from glucose, fatty acid and amino acids at the cellular level...

fatty acids with an odd number of carbons are modified by carboxylation of propionyl CoA to...

An individual has an excess of glucose and converts the glucose into fatty acids for better...

An individual has an excess of glucose and converts the glucose into fatty acids for better...

Both Glucose and Fatty Acids can be completely oxidized to CO2, with the energy release used...

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