In: Chemistry
fatty acids with an odd number of carbons are modified by carboxylation of propionyl CoA to ultimately generate the 4 carbon TCA intermediate_____ a. citric acid b. succinyl CoA c. Fumaric acid d. oxalic acid CoA e. Acetyl CoA
Dear friend your answer is b. succinyl CoA
Please see below for proof
Odd-numbered fatty
acids
Fatty acids with odd numbers of carbons are found in some marine
animals, in many herbivores, in microorganisms, and in plants.
These fatty acids are subjected to ?-oxidation in the same way as
fatty acids with even numbers of carbons. However, the final
?-oxidation spiral results in the production of the three-carbon
compound propionyl-CoA, which cannot be metabolized in the same way
as acetyl- CoA. Instead, propionyl-CoA is converted to
succinyl-CoA, a TCA cycle intermediate, via a three enzyme
pathway.
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