Question

Cystic Fibrosis is a disease caused by a defect in a Chloride ion transport channel protein. The channel performs a critical function in the lungs; thus, disease sufferers have trouble clearing mucous from their lungs, leaving them susceptible to opportunistic infections.

Discuss how this protein may function (normally) in the lung & hypothesize on possible treatment schemes.

Answer 1

In the various studies this idea is given that cystic fibrosis doesn't have a satisfactory treatment plan for the removal of cystic fibrosis disease. but we can control the symptoms of cystic fibrosis like:

1. Control and reduction of generation of mucus from the parts where mucus is formed.

2. removal of mucus from the parts of respiratory tract.

3. reduction of chances of infections occurred in the mucus by various infective agents.

4. Scientist developed some medicine which is used for alternative transport of chloride ions but it is not sufficiently described by scientist.

In other way for the normal production of protein we can use gene therapy or recombinent DNA technology.

in this we can transfer the gene with codes for the protein to the cell. after the entry of gene into the cell that incorporate itself into the nucleus and then allow the formation of normal protein which is responsible for chloride Ion transport.

generally gene therapy have lots of social ethical and moral issues so this therapy are not that much applicable in various circumstances.

for another way we can use stem cell injection for the formation of normal proteins but this method is now in studies.