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In: Biology

How is the HO gene controlled by SWI5 and SFB?  How does gene expression differ in the...

How is the HO gene controlled by SWI5 and SFB?  How does gene expression differ in the mother and daughter cells?

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Expert Solution

Regulation of HO Gene expression in yeast saccharomyces cerevisiae is intricately orchestrated by an assortment of Gene specific DNA binding and non DNA binding regulators. Binding of the early GAME transcription factors SWi5 to the distal URSI element of the HO promoter initiates a Cascade of events through recruitment of the SWi and SAGA complexes. In late G1 binding of transcription factors SBF to promoter proximal sequences results in the timely expression of HO.in this work we describe an important additional layer of complexity to the current model by identifying a connection between SWi5 and the mediator RNA polymerase 2 holoenzyme complex.

In terms of DNA content or the amount of DNA the daughter cells are identical to the parent. In organisms, mitosis is a way to produce two daughter cells that will have different functions become different cell types. The daughter cells still have the same amount of DNA as the parent cells. In mitosis , the daughter cells have the same number of chromosomes as the parent cell, while in meiosis, the daughter cells have half the number of chromosome as the parent.


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