Which of the following is NOT required for export of a protein from the nucleus to...

Which of the following is NOT required for export of a protein from the nucleus to the cytosol?

Group of answer choices

Ran-GDP

Nuclear export receptor

Ran-GTP

None of the above

Solutions

Expert Solution

Ran-GTP and exportin proteins binds to the cargo protein in nucleus and transport it to the cytoplasm via nucleopore. Once ethe entire complex is in cytosol a GTPase convert Ran-GTP into Ran-GDP this causes entire complex to dissociate from cargo proteins. Ran-GDP along with exportin is transferred back from cytosol to nucleus. So protein is successfully delivered to cytosol when Ran-GTP is converted to Ran-GDP. Ran-GDP is formed when protein is delivered to cytosol. So if Ran-GDP formation is blocked protein will never dissociate in cytosol. So all of them are required for transport from nucleus to cytosol.

Option D (none of the above) is correct. For only one cycle Ran-GDP also can be considered

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Which of the following is not true regarding mRNA splicing and mRNA export from the nucleus?...

Which of the following is not true regarding mRNA splicing and mRNA export from the nucleus? A. Spliced mRNA are exported with the assistance of the Ran pathway. B. An mRNA that undergo splicing is exported more rapidly than an identical mRNA which has the intron genetically removed. C. All of the given answers are true. D.Exon junction complexes assist in mRNA export. the answer for this is not C. The CRISPR/Cas system used in labs to modify many different...

In a Toll null mutant, in which cells will Dorsal protein be localized to the nucleus?...

In a Toll null mutant, in which cells will Dorsal protein be localized to the nucleus? Why? What is the resulting phenotype?

Compare and contrast protein import into the mitochondria and nucleus. Include the following terms in the...

Compare and contrast protein import into the mitochondria and nucleus. Include the following terms in the way that shows you understand differences in the import mechanisms: (1) translocation mechanism, (2) signal sequences (whether the signal sequence is cleaved following import) and (3) state of protein folding (whether the proteins are in an unfolded or folded state during the import).

A nucleus has atomic mass of 144. In which of the following cases could the nucleus...

A nucleus has atomic mass of 144. In which of the following cases could the nucleus be stable? A) The nucleus may be stable if it has between 73 and 83 protons. B) The nucleus may be stable if it has between 144 and 288 protons. C) The nucleus may be stable if it has between 83 and 144 protons D) The nucleus may be stable if it has more than 288 protons E) None of the the cases described...

RNA provides the genetic blueprint to produce a protein at which cellular structure? nucleolus ribosome nucleus...

RNA provides the genetic blueprint to produce a protein at which cellular structure? nucleolus ribosome nucleus smooth endoplasmic reticulum Select ALL of the features that a plant cell has but an animal cell does not. nucleolus chloroplast vacuole Golgi apparatus centrioles cell wall Select ALL of the features that eukaryotic cells have but prokaryotic cells do not. DNA ribosome endoplasmic reticulum mitochondrion nucleus Select ALL of the functions of a cell wall of a plant. Cell walls provide the plant...

How much protein is required? What does the book say about the required protein for a...

How much protein is required? What does the book say about the required protein for a healthy adult?

compare and contrast protein import into the ER and into the nucleus. List at least two...

compare and contrast protein import into the ER and into the nucleus. List at least two major differences in the mechanisms, and speculate why the ER mechanism might not work for nuclear import and vice versa.

Describe the process of protein synthesis starting with DNA in the nucleus and ending with proteins...

Describe the process of protein synthesis starting with DNA in the nucleus and ending with proteins released from the ribosomes. Include the role of the DNA, mRNA, tRNA, rRNA and amino acids.

In which orbital below would an electron (on average) be farthest from the nucleus?

In which orbital below would an electron (on average) be farthest from the nucleus? A) 3d B) 2p C) 1s D) 4f E) 3s

QUESTION 1 Which of the following particles are found in the nucleus of an atom? A....

QUESTION 1 Which of the following particles are found in the nucleus of an atom? A. protons and neutrons B. protons and electrons C. neutrons and electrons D. neutrons, electrons, and protons QUESTION 2 Which of the following best describes the atomic number of an atom? A. the number of protons in the atom B. the number of electrons in the atom C. the number of neutrons in the atom D. the number of protons, electrons, and neutrons in the...

Subjects