Which of the following is not a function of the glucocorticoids? A. preservation of carbohydrate reserves...

Which of the following is not a function of the glucocorticoids?

A. preservation of carbohydrate reserves

B. suppresion of inflammatory reactions

C. promotion of glucoconeogenesis

D. mobilization of fat

E. maintenance of normal blood level of calcium

Expert Solution

Ans: (E) Maintenance of normal blood level of calcium is not a function of the glucocorticoids.

Explanation: (A) Glucocorticoids helps in the preservation of carbohydrate reserves by inhibition of glucose uptake in muscles and adipose tissues.

(B) Glucocorticoids inhibits many of the initial events in an inflammatory response by reducing the expression of cytokines, chemokines, adhesion molecules and other inflammatory proteins. Further, it prevents the recruitment of inflammatory cells to the sites of inflammation leading to the suppresion of inflammatory reactions.

(C) Glucocorticoids causes stimulation of gluconeogenesis in liver resulting in the synthesis of glucose from non-hexose substrates such as triglycerides, fats etc.

(D) Glucocorticoids cause mobilization and redistribution of fats by three ways: (i) mobilization of fatty acids from adipose tissue, (ii) increasing the concentration of fatty acids in blood, and (iii) increasing the utilization of fats for energy.

(E) Glucocorticoids increases renal calcium excretion and decreases gastrointestinal calcium absorption, resulting in reduced serum calcium.

Sydney Mullin answered 1 year ago

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