Question

10. Fill in the blank: In vitro irradiation of macromolecules causes _____ damage to macromolecules. A) Repairable
    2. Reversible
    3. Irreversible
    4. Both A and B

10. Localized doses of 7 Gy to the skin can cause:
    1. Death
    2. Permanent hair loss
    3. Gastrointestinal syndrome
    4. All of the above

Answer 1

In vitro irradiation stands for the irradiation outside the cell or body. When macromolecules are irradiated in vitro, their viscosity may change, the molecule may undergo main chain scission or some cross linking. But all these changes can be either repaired or reversed once the radiation is stopped. So the appropriate choices here will be Repairable and Reversible, that is both A and B

Fill in the blank: In vitro irradiation of macromolecules causes _____ damage to macromolecules.

A) Repairable

B) Reversible

C) Irreversible

D) Both A and B

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Gy - Gray is defined as the energy transfer of 1 joule per Kg of the irradiated material.

7 Gy is 700 rads, localised doses of 7Gy to the skin may cause permanent hair loss within three weeks of exposure whereas acute doses of 3-6 Gy only causes temporary hair loss. Acute whole body exposures from 8 Gy to 30 Gy may cause Gastrointestinal Syndrome and sometimes death

Localized doses of 7 Gy to the skin can cause:

1. Death
2. Permanent hair loss
3. Gastrointestinal syndrome
4. All of the above