Question

6. Explain the process of non-muscle cell contractility. Which specific cytoskeletal molecules are involved? How would inhibition of depolymerization of cytoskeletal molecules affect this process?

Answer 1

Explain the process of non-muscle cell contractility. Which specific cytoskeletal molecules are involved? How would inhibition of depolymerization of cytoskeletal molecules affect this process?

In non muscle cells, there is an orderly movement of the myosin 2 filaments that results in motility. In non muscle cel, the cytoskeleton is zrrwnged in swt hrt b s manner along with the arrangement of the motor cells, that result in the movement of the non muscle cells. The cytoskeleton results in buffering of stresses thst srs oresenf in the external environment, provides the cells with the power of contractions. In the cytoskeleton, there occur constant assembling as well as disassembling of cables of protein. In the cytoskeleton, there had been visualisation of motor proteins which were present in organised patterns, and these were referred to as the stress fibers. The stress fibers are composed of a number of individual filaments, which are joined to one another by cross linking proteins.

Myosin II filaments get stacked, in the fibroblast cells, which forms the basis of cytoskeleton self organisation. Fibroblast requires that the cell has to be stretched so that there would be generation of cytoskeleton protrusion. As the myosin II assembly as well as organisation is done in the fibroblast cells, cellular processes would be regulated.

If depolymerisation is inhibited, there would einhibition of contractility of non muscle cells.