In: Statistics and Probability
A study is conducted in patients with HIV. The primary outcome
is CD4 cell count which is a measure of the stage of the disease.
Lower CD4 counts are associated with more advanced disease. The
investigators are interested in the association between vitamin and
mineral supplements and CD4 count. A multiple regression analysis
is performed relating CD4 count to use of supplements (coded as
1=yes, 0=no) and to duration of HIV, in years (i.e., the number of
years between the diagnosis of HIV and the study date). For the
analysis, Y=CD4 count.
Y
= 302 + 15.1 Supplements – 18.6 Duration of HIV
A) What is the expected CD4 count for a patient taking supplements
who has had HIV for 2.5 years? (5 points)
Y=
B) What is the expected CD4 count for a patient not taking
supplements who was diagnosed with HIV at study enrollment? (5
points)
Y =
C) What is the expected CD4 count for a patient not taking
supplements who has had HIV for 2.5 years. (5 points)
Y=
Sol:
Y = 302 + 15.1 Supplements – 18.6 Duration of HIV
A) What is the expected CD4 count for a patient taking
supplements who has had HIV for 2.5 years? (5 points)
Y= 302 + 15.1*(1) – 18.6*(2.5) = 363.6
B) What is the expected CD4 count for a patient not taking
supplements who was diagnosed with HIV at study enrollment? (5
points)
Y = 302 + 15.1*0 – 18.6*0 = 302
C) What is the expected CD4 count for a patient not taking
supplements who has had HIV for 2.5 years. (5 points)
Y= 302 + 15.1*0 – 18.6*2.5 = 348.5