Question
In: Biology
Research in cell biology and metabolism has progressed due to the discovery of molecules that artificially...
Research in cell biology and metabolism has progressed due to the discovery of molecules that artificially stimulate or inhibit glucagon/epinephrine and insulin signaling pathways. Let’s say you are working in a lab cataloging the effects of a library of small molecules on these pathways and have a “hit” on molecule 1stAVNGR. Preliminary data on molecule 1stAVNGRindicates that the cardiac isoform of PFK2/FBPase2 is doubly phosphorylated when this molecule is present at micromolar concentrations in cell cultures.
A. In consideration of the data presented in this problem what would be the expected effect of molecule 1stAVNGRon glycolytic flux in a culture of cardiac myocytes? Explain your reasoning?
B.Finally, if molecule 1stAVNGRwere infused into a culture of hepatocytes what would be the expected effect on glycolytic flux in these cells? Explain your reasoning.
Solutions
gladiator answered 1 year agoRelated Solutions
Research in cell biology and metabolism has progressed due to the discovery of molecules that artificially...
Research in cell biology and metabolism has progressed due to
the discovery of molecules that artificially stimulate or inhibit
glucagon/epinephrine and insulin signaling pathways. Let’s say you
are working in a lab cataloging the effects of a library of small
molecules on these pathways and have a “hit” on molecule 1stAVNGR.
Preliminary data on molecule 1stAVNGR indicates that the cardiac
isoform of PFK2/FBPase2 is doubly phosphorylated when this molecule
is present at micromolar concentrations in cell cultures. Given
this context...
Research in cell biology and metabolism has progressed due to the discovery of molecules that artificially...
Research in cell biology and metabolism has progressed due to
the discovery of molecules that artificially stimulate or inhibit
glucagon/epinephrine and insulin signaling pathways. Let’s say you
are working in a lab cataloging the effects of a library of small
molecules on these pathways and have a “hit” on molecule 1stAVNGR.
Preliminary data on molecule 1stAVNGR indicates that the cardiac
isoform of PFK2/FBPase2 is doubly phosphorylated when this molecule
is present at micromolar concentrations in cell cultures. Given
this context...
Research in cell biology and metabolism has progressed due to the discovery of molecules that artificially...
Research in cell biology and metabolism has progressed due to
the discovery of molecules that artificially stimulate or inhibit
glucagon/epinephrine and insulin signaling pathways. Let’s say you
are working in a lab cataloging the effects of a library of small
molecules on these pathways and have a “hit” on molecule 1stAVNGR.
Preliminary data on molecule 1stAVNGR indicates that the cardiac
isoform of PFK2/FBPase2 is doubly phosphorylated when this molecule
is present at micromolar concentrations in cell cultures. Given
this context...
Research in cell biology and metabolism has progressed due to the discovery of molecules that artificially...
Research in cell biology and metabolism has progressed due to
the discovery of molecules that artificially stimulate or inhibit
glucagon/epinephrine and insulin signaling pathways. Let’s say you
are working in a lab cataloging the effects of a library of small
molecules on these pathways and have a “hit” on molecule 1stAVNGR.
Preliminary data on molecule 1stAVNGR indicates that the cardiac
isoform of PFK2/FBPase2 is doubly phosphorylated when this molecule
is present at micromolar concentrations in cell cultures. Given
this context...
Let’s say a cell has arrested in the cell cycle due to a chromosome being temporarily...
Let’s say a cell has arrested in the cell cycle due to a
chromosome being temporarily unable to attach to the microtubules
of the mitotic spindle.
(a) At what stage of the cell cycle is the cell
arrested?
[
Select ]
["Prophase", "Metaphase",
"Prometaphase", "Anaphase"]
(b) For each of the factors listed below, decide if the factor
would be present in such a...
High in the Rocky Mountains, a biology research team has drained a lake to get rid...
High in the Rocky Mountains, a biology research team has drained
a lake to get rid of all fish. After the lake was refilled, they
stocked it with an endangered species of Greenback trout. Of the
2000 Greenback trout put into the lake 900 were tagged for later
study. An electroshock method is used on individual fish to get a
study sample. However, this method is hard on the fish. The
research team wants to know the smallest number of...
High in the Rocky Mountains, a biology research team has drained a lake to get rid...
High in the Rocky Mountains, a biology research team has drained
a lake to get rid of all fish. After the lake was refilled, they
stocked it with an endangered species of Greenback trout. Of the
2000 Greenback trout put into the lake 600 were tagged for later
study. An electroshock method is used on individual fish to get a
study sample. However, this method is hard on the fish. The
research team wants to know the smallest number of...
High in the Rocky Mountains, a biology research team has drained a lake to get rid...
High in the Rocky Mountains, a biology research team has drained
a lake to get rid of all fish. After the lake was refilled, they
stocked it with an endangered species of Greenback trout. Of the
2000 Greenback trout put into the lake 600 were tagged for later
study. An electroshock method is used on individual fish to get a
study sample. However, this method is hard on the fish. The
research team wants to know the smallest number of...
High in the Rocky Mountains, a biology research team has drained a lake to get rid...
High in the Rocky Mountains, a biology research team has drained
a lake to get rid of all fish. After the lake was refilled, they
stocked it with an endangered species of Greenback trout. Of the
2000 Greenback trout put into the lake 800 were tagged for later
study. An electroshock method is used on individual fish to get a
study sample. However, this method is hard on the fish. The
research team wants to know the smallest number of...
insert an If function in cell 5 to calculate the total due, if the student has...
insert an If function in cell 5 to calculate the total due, if
the student has chosen to personalize the ring there is an
additional charge of 5% located in cell B12 that must be applied:
if not the student only pays the base price. Use appropriate
relative and absolute cell references in excel
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