In: Biology
A new genomic method, TSA-Seq, developed by the Belmont laboratory derives similar but somewhat different information. The Belmont lab explains that whereas DamID measures “molecular contact frequency”, TSA-Seq measures “cytological distance”.
Explain how the TSA-Seq method works. INCLUDE in your answer an explanation for why the Belmont lab says that DamID measures molecular proximity but TSA-Seq measures cytological distance (cytological means distances that you would measure in a microscope- ie over ~100s of nm to micron).