In: Biology
What different strategies do microaerophilic and aerobic bacteria use to protect nitrogenase from oxygen?
Biological nitrogen fixation is catalyzed by nitrogenase, consisting of two proteins, dinitrogenase reductase (Fe protein) and dinitrogenase (MoFe protein). In aerobic bacterial species, two major mechanisms are believed to contribute to the protection of nitrogenase, increased respiration and conformational protection.
The nitrogenase enzyme complex (the nitrogen. fixing enzyme) is
sensitive to O2, that irreversible inactivates the enzyme.
Microaerophiles must employ mechanisms which on the other hand,l
permit the supply of O2 required for energy regeneration and
protect nitrogeNase from the deleterious effect of O2.
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