Question

Which of the following accurately complete the sentence? Steroid hormones _______ Group of answer choices More than one answer is correct

Use a signal transduction system to deliver their ‘message’ to the nucleus of the target cell

Cannot pass easily through the outer cell membrane of the target cell

Delivery their ‘message’ to a receptor in the outer cell membrane of the target cell

Bind directly to a gene regulatory protein in the nucleus of the target cell

Answer 1

Steroid hormones;

Use a signal transduction system to deliver their ‘message’ to the nucleus of the target cell.

Explanation- Steroid hormones like androgens, estrogens, glucocorticoids, mineralocorticoids, and progestins, bind with high affinity to their respective steroid hormone receptors (SR) which is present in the cytosol. In cytosol, it remains in inactive form after making complex with heat shock protein (HSP). Ligand binding with the receptor in the cytosol results in the dissociation of HSPs and translocation from the cytosol into the cell nucleus, where they bind to specific DNA sequences, hormone response elements.

Delivery their ‘message’ to a receptor in the outer cell membrane of the target cell.

Explanation- Some steroid receptors are associated with the plasma membrane. Steroid hormone binding to this plasma membrane steroid receptors activates G-protein coupled receptors (GPCR) and intracellular signaling pathways ultimately regulating gene transcription and other downstream events.

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