In: Biology
After paired chromosomes align at the cell's "equator", what happens to each of the chromosomes in mitosis?
In metaphase, the spindle has captured all the chromosomes and
lined them up at the middle of the cell, ready to divide.
All the chromosomes align at the metaphase plate.
At this stage, the two kinetochores of each chromosome should be
attached to microtubules from opposite spindle poles.
Before proceeding to anaphase, the cell will check to make sure that all the chromosomes are at the metaphase plate with their kinetochores correctly attached to microtubules. This is called the spindle checkpoint and helps ensure that the sister chromatids will split evenly between the two daughter cells when they separate in the next step. If a chromosome is not properly aligned or attached, the cell will halt division until the problem is fixed.
Anaphase is the stage of Mitosis after the process of metaphase when replicated chromosome are split and the newly copied chromosomes are moved to opposite poles of the cell.
Once Anaphase is completed the cell moves into telophase.
Tilophase is the final stage during which nuclear envelope is re-assembled around each set of chromatids, the nucleoli reappear and chromosome begin to decondense back into the expanded chromatin that is present during interphase.